ARMS Taq DNA Polymerase: Revolutionizing Amplification Refractory Mutation System (ARMS) PCR
Unleash the power of ARMS Taq DNA Polymerase, an exceptional enzyme specifically designed to optimize Amplification Refractory Mutation System (ARMS) PCR. Experience enhanced specificity, sensitivity, and robustness for the detection of single nucleotide polymorphisms (SNPs) and small insertions/deletions (indels) with ARMS Taq DNA Polymerase. Embrace the future of ARMS PCR with this groundbreaking enzyme and unlock new frontiers in molecular diagnostics.
Product Overview
Introducing ARMS Taq DNA Polymerase, a cutting-edge hot-start Taq enzyme revolutionized through antibody mediation and genetic engineering. This next-generation polymerase is meticulously designed to precisely recognize single-base mismatches at the 3' end of primers, unlocking unparalleled specificity in ARMS detection. With a recognition base strategically placed at the primer's 3' end, ARMS Taq DNA Polymerase achieves highly specific and sensitive detection, making it a versatile choice for both fluorescent PCR and advanced digital PCR platforms.
Key Features
- High Sensitivity and Specificity: Unrivaled accuracy in detecting single-base mismatches.
- Strong Blocking Ability: Effective performance in ARMS-PCR-mediated genotyping applications.
- Recognition Base at the 3' End: Precision engineering for enhanced specificity.
- Good Impurity Tolerance: Versatility for various detection scenarios.
Applications
- qPCR (Quantitative Polymerase Chain Reaction): Unprecedented accuracy in quantitative analysis.
- Genotyping: Reliable and efficient determination of genetic variations.
- SNP Analysis (Single Nucleotide Polymorphism): Precise identification of genetic variations at the single-nucleotide level.
Product Data
- Sensitivity and Specificity: Unmatched performance metrics to ensure reliable and accurate results.
Single base mutation detection
ARMS Taq DNA Polymerase: Unleashing Precision in ARMS PCR
In the realm of molecular diagnostics, the Amplification Refractory Mutation System (ARMS) PCR stands as a cornerstone technique, enabling the detection of single nucleotide polymorphisms (SNPs) and small insertions/deletions (indels) with remarkable accuracy. However, the performance of ARMS PCR can be significantly influenced by the choice of DNA polymerase. To address this critical aspect, ARMS Taq DNA Polymerase emerges as a game-changer, offering exceptional specificity, sensitivity, and robustness for ARMS PCR applications.
Enhanced Specificity for Error-Free SNP Detection
ARMS Taq DNA Polymerase exhibits remarkable specificity, minimizing mispriming and ensuring accurate detection of SNPs and indels. Its ability to discriminate between closely matched sequences makes it an invaluable tool for reliable genotyping and mutation analysis.
Unparalleled Sensitivity for Low-Abundant Targets
ARMS Taq DNA Polymerase boasts exceptional sensitivity, enabling the detection of even the faintest traces of mutant DNA. This remarkable sensitivity makes it suitable for a wide range of applications, including the analysis of low-abundance samples and the detection of rare mutations.
Robust Performance for Consistent Results
ARMS Taq DNA Polymerase delivers consistent and reliable performance across a wide range of experimental conditions. Its robustness ensures reproducible results and minimizes the risk of false positives or negatives.
Streamlined ARMS PCR Workflow
ARMS Taq DNA Polymerase integrates seamlessly into ARMS PCR protocols, streamlining your workflow and minimizing potential errors. Its exceptional performance eliminates the need for optimization, saving you valuable time and effort.
Unleashing the Power of ARMS PCR
ARMS Taq DNA Polymerase empowers researchers to harness the full potential of ARMS PCR, enabling the accurate and reliable detection of SNPs and indels in diverse applications, including:
- Genetic disease diagnosis
- Pharmacogenetic testing
- Forensic analysis
- Agricultural research
- Evolutionary studies
Embrace the future of ARMS PCR with ARMS Taq DNA Polymerase and revolutionize your molecular diagnostics endeavors. This groundbreaking enzyme offers unparalleled precision, sensitivity, and robustness, empowering you to unlock new frontiers in genetic research and clinical diagnostics.
Experience the transformative power of ARMS Taq DNA Polymerase and elevate your ARMS PCR experiments to new heights of accuracy and efficiency.
| Property | Value |
|---|---|
| Product Name | ARMS Taq DNA Polymerase |
| Source | Recombinant expression in Escherichia coli |
| Catalog Number | CSB-DEM073 |
| Physical Form | Liquid |
| Enzyme Activity | 5 U/μL |
| Storage Conditions | -20 ±5°C |
| Storage Buffer | 10 mM Tris-HCl, 100 mM KCl, 1 mM DTT, 0.1 mM EDTA, 0.5% Tween20, 0.5% NP-40, 50% Glycerol |
| Activity Definition | Within 30 minutes at 72°C, the amount of enzyme required to incorporate 10 nmol of deoxynucleotides into acid-insoluble material is 1 unit (U). |
| Quality Control | No residual nucleases and exonucleases |
| Shelf Life | 24 months |
Product Description
Elevate your PCR applications with ARMS Taq DNA Polymerase, a state-of-the-art hot-start enzyme that combines the benefits of upgraded recombination and antibody modification. This advanced polymerase not only retains high DNA polymerase activity but also boasts several times the specificity of conventional Taq enzymes. The precision is further enhanced by its hot-start feature, ensuring minimal background amplification.
Designed with meticulous attention to detail, ARMS Taq DNA Polymerase demonstrates robust performance with an optimized buffer system, showcasing potent blocking ability and maximizing mismatch recognition. This makes it particularly well-suited for applications requiring high specificity, such as the detection of related alleles in ARMS-PCR.
Product Components
| Label | Component Name | Specifications |
|---|---|---|
| 1 | 5× ARMS PCR buffer | 1.2 mL, 6 mL, 12 mL |
| 2 | ARMS Taq DNA Polymerase | 500 U, 2500 U, 5000 U |